Genomic response to selection for postponed senescence in Drosophila

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The Genomic Basis of Postponed Senescence in Drosophila melanogaster

Natural populations harbor considerable genetic variation for lifespan. While evolutionary theory provides general explanations for the existence of this variation, our knowledge of the genes harboring naturally occurring polymorphisms affecting lifespan is limited. Here, we assessed the genetic divergence between five Drosophila melanogaster lines selected for postponed senescence for over 170...

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Laboratory Evolution of Postponed Senescence in Drosophila Melanogaster.

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The Evolution of Development in Drosophila Melanogaster Selected for Postponed Senescence.

The role of development in the evolution of postponed senescence is poorly understood despite the existence of a major gerontological theory connecting developmental rate to aging. We investigate the role of developmental rate in the laboratory evolution of aging using 24 distinct populations of Drosophila melanogaster. We have found a significant difference between the larval developmental rat...

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The Japanese quail has been utilized as a research species in establishing the genetic relationships that may also be present in other species. Divergent phenotypic selection for 4-wk BW was conducted for three generations in high (HW) and low (LW) lines. Within each line, 50 females and 25 males were selected among 600 birds, based on 4-wk BW. Mean BW at 4 wk of age in the base generation was ...

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ژورنال

عنوان ژورنال: Mechanisms of Ageing and Development

سال: 2013

ISSN: 0047-6374

DOI: 10.1016/j.mad.2012.11.003